The liver is responsible for handling various metabolic functions in the body. Not only just, but the liver also detoxifies the blood and is responsible for processing different waste products in the hemoglobin.
To conduct all of these functions properly, the liver produces and secretes several types of enzymes for optimal regulation. SGOT or Serum glutamic oxaloacetic transaminase and SGPT or Serum glutamate pyruvate transaminase are two of the most common enzymes produced by the liver.
SGPT test, or Serum Glutamic Pyruvic Transaminase, is a blood test that can be used to detect any liver problems. It is commonly used to measure the level of a specific enzyme called ALT. If a patient has a high level of ALT, it may indicate that his liver has been damaged. However, a lower SGPT level is usually a sign that his liver is functioning properly. The SGPT test is performed by obtaining a blood sample from a vein in the arm. This sample is then analyzed by a qualified technician at a laboratory. A test report is then generated, which will provide the results in units per litre of blood. The test results are useful in detecting liver diseases and in diagnosing hepatitis. It is also used in monitoring the effects of medicines that may damage the liver. It is a painless procedure, and it does not require special preparation. Typically, the test can be performed within five minutes.
Your doctor will prescribe getting an SGPT & SGOT test to analyze your liver function and rule out possible complications.
Our liver partakes in several physiological functions. Experiencing vomiting, nausea, fatigue, leg swelling, jaundice, excessive bleeding or bruising could be an early sign of liver dysfunction. Don't brush these alarming symptoms under the rug. Instead, consult a doctor and get tested without any delay. Make the right decision today for a healthier tomorrow.
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This article will explore more about these enzymes, the significance of the test, and the test results.
In this Article
- What is SGPT and SGOT?
- What are the symptoms of elevated SGPT and SGOT levels?
- What are normal levels of AST (SGOT) and ALT (SGPT)?
- What do Elevated SGPT and SGOT levels Indicate?
- Are SGPT and SGOT Indicative of Liver Disease only?
- How can I prepare for the SGPT/SGOT Blood test?
- Are there any risks associated with the SGPT/SGOT blood tests?
- What do the Abnormal Test results Indicate?
- What is the cost of the SGPT-SGOT Blood test in India?
- Conclusion
What is SGPT and SGOT?
SGPT and SGOT are two of the most common types of liver enzymes.
Besides the liver, SGOT is found in the kidney, muscles, heart and even the brain. On the contrary, SGPT is predominantly found in the liver only.
Elevated levels of either of the enzymes can result from:
- SGOT levels can rise during liver complications, heart attacks or muscle injuries.
- SGPT levels can rise during liver diseases and damage to the tissues in the liver.
The SGPT levels are more inclined towards determining liver diseases and damage due to its elevated levels.
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What are the symptoms of elevated SGPT and SGOT levels?
If you see a doctor with the following symptoms, they might suggest undergoing the SGPT & SGOT tests. Some common danger level of SGPT and SGOT symptoms include:
- Constant feelings of fatigue and tiredness
- Vomiting and nausea
- Swelling in the leg
- Shortness of breath
- Jaundice
- Bruising quickly
Experiencing these symptoms is a warning sign that you need immediate medical intervention. If the test reports come back with high SGOT and SGPT levels, your doctor will move ahead with further testing or proceed with the treatment.
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What are normal levels of AST (SGOT) and ALT (SGPT)?
The normal ranges of SGOT and SGPT are standard. However, the range can slightly vary, depending on the testing method in the laboratory.
- Normal SGOT levels – 5 to 40 units per liter of serum
- Normal SGPT levels – 7 to 56 units per liter of serum
If the blood test reports are drastically different than the normal range, it can signify potent complications in the body, especially with liver diseases and disorders.
What do Elevated SGPT and SGOT levels Indicate?
Since SGPT and SGOT are quintessential enzymes produced in the liver, it isn’t surprising that altered levels of these enzymes indicate signs of liver damage.
The high levels are often indicative of several underlying complications in the body. Elevated levels of these enzymes aren’t SOLELY related to liver damage or disease. It can mean other complications too.
In some cases, the danger level of SGPT and SGOT indicate muscle damage or muscle diseases. The results from the blood test reports of SGPT and SGOT cannot accurately determine the degree of liver disease or damage in the patient.
Are SGPT and SGOT Indicative of Liver Disease only?
As we mentioned, that isn’t the case at all. Lower or elevated SGPT and SGOT enzymes aren’t just tied with liver disease or liver function.
Sometimes, patients with elevated levels of these two enzymes have an optimal liver function. It can be the complete opposite as well.
How can I prepare for the SGPT/SGOT Blood test?
The SGPT/SGOT blood tests are a part of the liver function test and are routine blood test that doesn’t require excessive prepping. The patients don’t have to fast or worry about the day when the blood is drawn.
However, for accurate results, we’d recommend discussing the medications you take. Since medications can alter the final reports, your doctor might advise getting the blood drawn before taking the medications.
The phlebotomist will collect the blood sample from the veins in your forearm after disinfecting the area. The collected sample is then sent for further testing to the laboratories.
Are there any risks associated with the SGPT/SGOT blood tests?
The SGPT/SGOT assessment in the body is done using a blood test. This means that the risks associated with these routine blood tests are very low and sometimes non-existent.
However, in very rare cases, some of the common risks might include:
- Excessive bleeding at the puncture site
- Hematoma or clotted blood underneath the skin
- Feeling lightheaded
- Infection
What do the Abnormal Test results Indicate?
Abnormal SGPT-SGOT levels in the bloodstream can be indicative of several complications, including:
- Hepatitis
- Liver cirrhosis
- Liver tissue damage
- Liver cancer
- Tumor in the liver
- Obstructed blood flow to the liver
- Hemochromatosis or iron build-up in the bloodstream
- Mononucleosis caused by Epstein-Barr virus
- Pancreatitis
If you have lower SGPT-SGOT levels in the bloodstream, that indicates a healthy liver. Unlike other markers, a low level, in this case, doesn’t signify anything alarming.
What is the cost of the SGPT-SGOT Blood test in India?
The SGPT-SGOT blood test in India typically starts from INR 80 each. The price will vary depending on the city and the laboratory the test is done in.
What is the alarming level of SGOT and SGPT?
The normal levels of SGPT usually must lie between 7-56 units/liter of serum. However, if the level of SGPT shows more than 56 units/ liter in the patient’s blood test, then that is referred to as an alarming level.
The normal level of SGOT usually must lie between 8-45 units/ liter of the serum. However, anything above 50 units/liter for men and above 45 units/ liter for women can be considered as alarming. The high levels of SGOT and SGPT often indicate severe underlying complications for the patients.The elevated levels can indicate damage or injury to the liver. It can also be an indicator of other complications related to muscle diseases and muscle damage as well.
What is the SGPT & SGOT
SGPT and SGOT are blood tests that indicate the status of your liver. If you have elevated levels of these two enzymes, your doctor may conduct further testing to determine if you have liver disease. This test can also be used to monitor the progress of treatment for liver disease. The SGPT normal range and SGOT normal ranges lie usually between 7 and 56 units per liter of blood serum. These ranges vary from laboratory to laboratory and depend on the methods used to measure the test. Serum Glutamic Pyruvic Transaminase (SGPT) is a liver enzyme that is present in several body tissues. The enzyme is needed for energy production. It is found in the liver and heart cells. During an SGPT/SGOT blood test, a blood sample is drawn from the vein in the arm. The results will be listed in the report. If your SGOT/SGPT ratio is more than two units, it is a sign that your liver is cirrhotic. This is a symptom of liver diseases such as alcoholic hepatitis.
normal range?
SGPT (serum glutamic pyruvic transaminase) is a liver enzyme, also known as alanine transaminase (ALT). The normal range for SGPT levels in the blood is typically between 7 and 56 units per liter (U/L). Anything above the SGPT normal range mentioned here can be alarming for the patient. Elevated levels of SGPT in the blood can be a sign of liver damage or disease. It is important to have liver function tests done regularly to monitor the health of the liver. It is recommended to consult with your doctor to determine what your specific SGPT levels mean in relation to your overall health.
Conclusion
SGPT and SGOT are key markers of liver function. If your doctor has prescribed these tests, it can indicate that they want to assess the state of your liver function along with other allied physiological functions. This routine blood test doesn’t come with any prominent risks or side effects.
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FAQs
What is SGOT and SGPT and normal levels? ›
Normal levels of SGOT: 5-40 units/liter of serum. what are elevated levels of SGOT and SGPT? SGPT is present predominantly in the liver and when it is produced in excess, it leaks into the bloodstream. The normal range of SGPT is about 7 to 56 units / liters of blood serum.
What does it mean if SGPT is high and SGOT is normal? ›What could be a medical condition if SGPT is high but SGOT is normal? A high SGPT and normal SGOT may suggest the existence of medical conditions like viral hepatitis, diabetes, infectious mononucleosis, non-alcoholic fatty liver disease, or bile duct problems.
What is the normal level of SGPT and SGPT? ›Normal Range of SGPT and SGOT
The SGPT and SGOT normal levels are as follows: SGPT / ALT (Alanine transaminase): 7 - 56 units per litre (U/L) in adults. SGOT / AST (Aspartate transaminase): 8 - 40 units per litre (U/L) in adults.
SGPT (serum glutamic-pyruvic transaminase) and SGOT (serum glutamic-oxaloacetic transaminase) are the enzymes produced by your liver and its cells. These enzymes are generally present within liver cells and to a lesser extent in the muscle cells.
What level of SGOT indicates liver cirrhosis? ›An SGOT/SGPT ratio greater than 2 is highly suggestive of alcoholic hepatitis and cirrhosis. It occurs in 70% of these patients compared with 26% of patients with postnecrotic cirrhosis, 8% with chronic hepatitis, 4% with viral hepatitis and none with obstructive jaundice.
What level of AST indicates liver damage? ›A normal AST:ALT ratio should be <1. In patients with alcoholic liver disease, the AST:ALT ratio is >1 in 92% of patients, and >2 in 70%. AST:ALT scores >2 are, therefore, strongly suggestive of alcoholic liver disease and scores <1 more suggestive of NAFLD/NASH.
Does SGOT and SGPT indicate fatty liver? ›How can fatty liver easily be identified? Fat in the liver usually does not produce any specific signs or symptoms. Occasionally patients will experience a dull pain in the right upper abdomen. Blood tests may reveal an elevation of the liver chemistries (SGOT or AST, SGPT or ALT, GGT, Alkaline phosphatase).
Can fatty liver raise SGPT? ›SGpt Rises dramatically in acute liver damage. Elevated liver biochemical test levels may be found in up to 50% of patients with simple steatosis and are present in 80% of patient with advanced NAFLD.
What blood test shows liver function? ›Alanine transaminase (ALT) test.
This test may be performed to assess liver function, and/or to evaluate treatment of acute liver disease, such as hepatitis.
Normal blood test results for typical liver function tests include: ALT. 7 to 55 units per liter (U/L) AST. 8 to 48 U/L.
What is the alarming level of SGPT? ›
What is the alarming level of SGPT? Anything beyond 56 units per litre is considered abnormal. However, if your test results show that your SGPT levels have risen beyond 65, then this could be deemed as alarming levels of SGPT.
What is an alarming AST level? ›...
Normal AST ranges.
| Adults | Children | |
|---|---|---|
| High | >36 U/L >1,000 U/L are very high levels and may be a sign of liver injury or hepatitis | >40 IU/L which may be a sign of liver inflammation |
If you have fatty liver disease, the damage may be reversed if you abstain from alcohol for a period of time (this could be months or years). After this point, it's usually safe to start drinking again if you stick to the NHS guidelines on alcohol units. However, it's important to check with your doctor first.
What is the danger level of SGPT and SGOT treatment? ›However, anything above 50 units/liter for men and above 45 units/ liter for women can be considered as alarming. The high levels of SGOT and SGPT often indicate severe underlying complications for the patients.The elevated levels can indicate damage or injury to the liver.
What blood tests confirm cirrhosis? ›Tests to confirm a diagnosis of cirrhosis include a complete blood count (CBC), liver enzyme, liver function and electrolyte testing as well as screening for other health conditions such as hepatitis B and C viruses, liver cancer or gallstones. In most cases, a liver biopsy is used to confirm the diagnosis.
What are your liver enzymes if you have cirrhosis? ›Patients with cirrhosis often have normal or only slightly elevated serum AST and ALT levels. Thus, AST and ALT lack some sensitivity in detecting chronic liver injury.
What are the 4 warning signs of a damaged liver? ›yellowing of the skin or whites of the eyes (jaundice) swelling in the legs, ankles and feet caused by a build-up of fluid (oedema) swelling in your abdomen caused by a build-up of fluid known as ascites. a high temperature and shivering attacks.
What numbers indicate fatty liver? ›In a community-based study of 1346 Japanese patients with diagnostic criteria of NAFLD, the cutoff value of ALT for diagnosis of this disease was estimated to be 25 U/L in men and 17 U/L in women[39]. For the BAAT score, a normal range of ALT is considered between 1 and 19[27].
What level of ALT means liver damage? ›ALT levels greater than 15 times the normal range indicate severe acute liver cell injury and evaluation should be initiated immediately. The differential diagnosis for patients with severe acute liver injury (ALT levels >15 times the normal range) is relatively limited.
What foods cause high SGPT? ›- Alcohol. Alcohol can be a major cause of fatty liver disease as well as other liver diseases.
- Added sugar. Stay away from sugary foods such as candy, cookies, sodas, and fruit juices. ...
- Fried foods. ...
- Added salt. ...
- White bread, rice, and pasta. ...
- Red meat.
What is the symptoms of SGOT SGPT high? ›
...
What are the symptoms of the high level of SGPT?
- Jaundice.
- Easy bruising.
- Excessive bleeding.
- Shortness in breath.
- Swelling in the leg area.
- Fatigue.
- Weakness.
- Nausea and vomiting.
These include your liver, but also the muscles, heart, brain, and kidneys. Your doctor may order follow-up tests to rule out another diagnosis. The normal range of an SGOT test is generally between 8 and 45 units per liter of serum.
What medicine is good for high SGPT? ›In contrast, the addition of hydroxychloroquine to a regimen of either MTX or aspirin essentially eliminated the SGOT and SGPT abnormalities.
Can fatty liver be cured? ›The good news is that fatty liver disease can be reversed—and even cured—if patients take action, including a 10% sustained loss in body weight.
What happens when SGPT is high? ›SGPT is released into blood when the liver or heart are damaged. The blood SGPT levels are thus elevated with liver damage (for example, from viral hepatitis) or with an insult to the heart (for example, from a heart attack). Some medications can also raise SGPT levels. Also called alanine aminotransferase (ALT).
Can a blood test tell if your liver is OK? ›A total protein test measures levels of protein in your blood. Your liver makes protein, and low protein levels may indicate that your liver isn't functioning optimally. Bilirubin test.
What can I drink to flush my liver? ›- Chamomile Tea. This tea is mildly bitter due to its sesquiterpene lactone content which helps the liver prime its detoxification pathways. ...
- Lemon Water. ...
- Jujube Fruit. ...
- Lotus Seed. ...
- Rose Tea. ...
- Peppermint Tea. ...
- Oat Tea. ...
- Schizandra Berry Tea.
- Skin and eyes that appear yellowish (jaundice)
- Abdominal pain and swelling.
- Swelling in the legs and ankles.
- Itchy skin.
- Dark urine color.
- Pale stool color.
- Chronic fatigue.
- Nausea or vomiting.
Critical value:
>9000 U/L seen in Alcohol-acetaminophen syndrome. This level can distinguish it from alcoholic or viral hepatitis.
The sgpt normal range is about 7 to 56 units per liter of blood serum. Thus, very high level of sgpt in the blood can be an indication of damage or problems related to the liver.
What is the SGPT level of fatty liver? ›
Elevated liver biochemical test levels may be found in up to 50% of patients with simple steatosis and are present in 80% of patient with advanced NAFLD. The wavelength of 340 nm green bilter paper can be used to estimate the SGPT. The normal value of SGPT are 5 to 45 IU/L.
What is the main cause of high SGPT? ›A high level of SGPT released into the blood may be a sign of liver damage, cancer, or other diseases. Also called alanine transferase and serum glutamate pyruvate transaminase.
What are symptoms of high SGPT? ›- Weakness.
- Nausea.
- Fatigue.
- Vomiting.
- Shortness of breath.
- Swelling in legs.
- Jaundice.
- Excessive bleeding.
What foods are good for liver repair? Many foods contain specific compounds or antioxidants that have been shown to support liver function. A few examples include grapefruit, blueberries, cranberries, fatty fish, olive oil, and cruciferous vegetables like broccoli or Brussels sprouts.
Does fatty liver cause high SGOT? ›Fat in the liver usually does not produce any specific signs or symptoms. Occasionally patients will experience a dull pain in the right upper abdomen. Blood tests may reveal an elevation of the liver chemistries (SGOT or AST, SGPT or ALT, GGT, Alkaline phosphatase).
When should I be concerned about SGOT levels? ›The normal range of an SGOT test is generally between 8 and 45 units per liter of serum. In general, men may naturally have higher amounts of AST in the blood. A score above 50 for men and 45 for women is high and may indicate damage.
What is the normal range of liver function test? ›Normal blood test results for typical liver function tests include: ALT. 7 to 55 units per liter (U/L) AST. 8 to 48 U/L.
What medication is used for high SGPT? ›In contrast, the addition of hydroxychloroquine to a regimen of either MTX or aspirin essentially eliminated the SGOT and SGPT abnormalities.
What does SGOT mean in medical terms? ›An enzyme found in the liver, heart, and other tissues. A high level of SGOT released into the blood may be a sign of liver or heart damage, cancer, or other diseases. Also called aspartate transaminase and serum glutamic-oxaloacetic transaminase.
What food causes high SGPT? ›- Alcohol. Alcohol can be a major cause of fatty liver disease as well as other liver diseases.
- Added sugar. Stay away from sugary foods such as candy, cookies, sodas, and fruit juices. ...
- Fried foods. ...
- Added salt. ...
- White bread, rice, and pasta. ...
- Red meat.